President Kirkman is faced with a viral pandemic that threatens to kill countless Americans, while FBI Agent Hannah Wells and MI-6 Agent Damian Rennett discover evidence that could change the lives of members of the first family forever.
- Kiefer Sutherland as Tom Kirkman
- Natascha McElhone as Alex Kirkman
- Paulo Costanzo as Lyor Boone
- Adan Canto as Aaron Shore
- Italia Ricci as Emily Rhodes
- LaMonica Garrett as Mike Ritter
- Zoe McLellan as Kendra Daynes
- Ben Larson as Damian Rennett
- Kal Penn as Seth Wright
- Maggie Q as Hannah Wells
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